Surface modification, functionalization and integration of microfluidics and biosensor to form a biochip
US8951716B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | Mar 30, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/0887
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure provides methods of fabricating a biochip. The biochip includes a fluidic part, having through-substrate holes as inlets and outlets, and a sensing part bonded together using a bonding material. One or both of the parts has microfluidic channel patterns and one or more patterned surface modification layers formed using different methods to provide surface property for binding bioreceptors and for flowing analytes. The patterning includes lithography, etching, washing, selective depositing using printing or self-assembly of surface chemistry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.