Malonate decarboxylases for industrial applications
US8951750B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Nov 28, 2008 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | Aug 30, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the enzymatic decarboxylation of malonic acid (propanedioic acid) derivatives catalyzed by enzymes structurally and/or functionally related to arylmalonate decarboxylase (AMDase) as isolated from microorganisms of the genus Bordetella. The present invention also relates to novel enzymes with a decarboxylase activity, useful for performing the claimed method, mutants thereof, corresponding coding sequences and expression systems, methods of preparing said novel enzymes, and screening methods for obtaining further suitable enzymes also having said decarboxylase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.