CXCR3 receptor antagonists

US8952004B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• John David Ginn · New Milford, US
• Ronald John Sorcek · Bethel, US
• Michael Robert Turner · Danbury, US
• Di Wu · Danbury, US
• Frank Wu · Shandong, CN

Key dates

• Filing date: Jan 5, 2011
• Grant date: Feb 10, 2015
• Expiry date: May 15, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D497/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein R1 to R3, A, B, X, and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.