Chroman derivatives as TRPM8 inhibitors
US8952009B2 · kind B2 · utility
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Key dates
| Filing date | Aug 2, 2013 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | Aug 2, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Chroman compounds and derivatives of Formula I are useful inhibitors of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure:where the definitions of the variables are provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.