Patent · US Active

Designer osteogenic proteins

US8952131B2 · kind B2 · utility

7Cited by

38References

10Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Stephen Berasi · Arlington, US
Robert Vincent Martinez · Carlisle, US
Michael John Cain · Exeter, US
John M. Wozney · Hudson, US
Howard Seeherman · Cambridge, US
Z. Sean Juo · Cambridge, US
Valerie Calabro · Ponteau, FR
Christopher BROWN · Chelmsford, US

Key dates

Filing date	Aug 17, 2011
Grant date	Feb 10, 2015
Priority date	—
Expiry date	Aug 17, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.