Process for the preparation of β-C-aryl glucosides
US8952139B2 · kind B2 · utility
3Cited by
1References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 7, 2012 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | May 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes (e.g., arylation reaction) for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors. A representative process of the present application includes the preparation of the compound of formula IV starting from a compound of the formula II with a metalated aryl compound, as disclosed below:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.