Isothiazole-pyridine derivatives as modulators of HIF (hypoxia inducible factor) activity
US8952160B2 · kind B2 · utility
15Cited by
7References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2009 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | Apr 22, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds according to Formula I or II, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF). Formula (I) or (II).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.