Copper-catalyzed C—H bond arylation
US8952207B2 · kind B2 · utility
2Cited by
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12Claims
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Key dates
| Filing date | Sep 10, 2008 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | May 23, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is a one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using a combination of aryl halides, a substrate, and a copper salt as catalyst. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores and explosives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.