Magnetic particle imaging (MPI) system and method for use of iron-based nanoparticles in imaging and diagnosis
US8954131B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 26, 2010 |
| Grant date | Feb 10, 2015 |
| Priority date | — |
| Expiry date | Sep 25, 2032 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01F1/0045
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for diagnosing certain types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period passes to allow the nanoparticles to be uptaken by the cancer cells. Imaging is then performed on the nanoparticles by an appropriate imaging device to determine the concentration of nanoparticles uptaken by the cancer cells. Finally, image data provided by the imaging device is analyzed to determine the concentration of nanoparticles and thereby determine whether a tumor is present. The nanoparticle agent can further be employed as a treatment of certain cancers. After the uptake of nanoparticles into the cells, a predetermined field applied to the nanoparticles for a sufficient period of time activates the magnetic cores of the nanoparticles to include hyperthermia-mediated destruction of the cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.