Patent · US Active

BACE1 inhibitory antibodies

US8956614B2 · kind B2 · utility

1Cited by

7References

29Claims

0Family size

Assignees

VIB VZW · BE
Katholieke Universiteit Leuven, KU LEUVEN R&D · BE

Inventors

Bart De Strooper · Leuven, BE
Lujia Zhou · Leuven, BE
Wim Annaert · Kontich, BE

Key dates

Filing date	Jun 15, 2010
Grant date	Feb 17, 2015
Priority date	—
Expiry date	Jan 18, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to antibodies with a specificity for BACE1. More specifically, the invention provides monoclonal antibodies that bind to BACE1 and are capable of inhibiting the activity of BACE1 and methods producing these antibodies. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.