Compositions and methods for treatment of cervical dysplasia
US8956621B2 · kind B2 · utility
14Cited by
30References
26Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 8, 2011 |
| Grant date | Feb 17, 2015 |
| Priority date | — |
| Expiry date | Nov 20, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of treating, protecting against, and inducing an immune response against cervical dysplasia and cancer, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and an E7 and/or E6 antigen. The present invention also provides methods for inducing an anti-E7 CTL response in a human subject and treating HPV-mediated diseases, disorders, and symptoms, comprising administration of the recombinant Listeria strain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.