Fungal xylanases and xylosidases

US8956844B2 · kind B2 · utility

Assignee

• Codexis, Inc. · US

Inventors

• Nicholas J. Agard · San Francisco, US
• David Elgart · San Mateo, US
• Jie Yang · Foster City, US
• Goutami Banerjee · Hayward, US
• Jeanne Bonomo Benoit · Menlo Park, US
• Dipnath Baidyaroy · Fremont, US

Key dates

• Filing date: Jun 10, 2013
• Grant date: Feb 17, 2015
• Expiry date: Jun 10, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02E50/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides fungal xylanase and/or xylosidase enzymes suitable for use in saccharification reactions. The present invention provides xylanase and xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase(s) and/or xylosidase(s), as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures. In some embodiments, the xylanase and xylosidase enzyme(s) are M. thermophila enzymes.