Gamma secretase inhibitor for treatment of herpesvirus infection
US8957012B2 · kind B2 · utility
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1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 24, 2012 |
| Grant date | Feb 17, 2015 |
| Priority date | — |
| Expiry date | Jan 24, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby arresting the growth of the infected cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.