Patent · US Active

Compounds and compositions as protein kinase inhibitors

US8957081B2 · kind B2 · utility

3Cited by
17References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 11, 2012
Grant dateFeb 17, 2015
Priority date
Expiry dateSep 11, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.