Isatin derivatives for use as in vivo imaging agents
US8961930B2 · kind B2 · utility
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Key dates
| Filing date | Sep 4, 2009 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Nov 21, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.