Orally bioavailable lipid-based constructs
US8962015B2 · kind B2 · utility
5Cited by
8References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2007 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Oct 10, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is embodied by a composition capable of chaperoning a typically non-orally available therapeutic or diagnostic agent through the environment of the digestive tract such that the therapeutic or diagnostic agent is bioavailable. The composition may or may not be targeted to specific cellular receptors, such as hepatocytes. Therapeutic agents include, but are not limited to, insulin, calcitonin, serotonin, and other proteins. Targeting is accomplished with biotin or metal based targeting agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.