Dicalcium phosphate ceramics, dicalcium phosphate/hydroxyapatite biphasic ceramics and method of manufacturing the same
US8962037B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2011 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Jul 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC04B2235/606
- WIPO fieldMaterials, metallurgy
- WIPO sectorChemistry
Abstract
The present invention discloses a method of manufacturing pure dicalcium phosphate ceramics or dicalcium phosphate/hydroxyapaite (HA) biphasic ceramics for medical applications in hard tissue areas to be used as implant materials. These ceramic implant materials are in granular form or in block form, and are prepared by using an acidic phosphate compound, a basic calcium phosphate compound comprising HA, and water. The dicalcium phosphate ceramic comprises either dicalcium phosphate dihydrate (CaHPO4.2H2O, DCPD) or dicalcium anhydrous (CaHPO4, DCPA). Wherein, when the acidic phosphate compound is provided in an amount stoichiometrically equal to or in excess relative to the basic calcium phosphate compound, a reaction product is the DCPD or DCPA ceramic; when the acidic phosphate compound is provided in the amount stoichiometrically less than the basic calcium phosphate compound, the reaction product is the DCPD/HA or DCPA/HA biphasic ceramic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.