Fluorescent probe compounds, preparation method and application thereof
US8962339B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 6, 2010 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Dec 15, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/7786
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2+ in near-neutral pH range. In detection of Pd2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.