Peptides involved in the SCF c-Kit signaling pathway and compositions comprising same
US8962565B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 30, 2012 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Jan 30, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptide compounds of general formula (I) R1-(AA)n-X1—X2—X3-Asp-Leu-Lys-Lys-X4—X5-(AA)p-R2, cosmetic or pharmaceutical compositions comprising at least one peptide compound of general formula (I) in a physiologically acceptable medium, and methods for cosmetic treatment of skin are disclosed. The peptide compounds of general formula (I) were demonstrated to be agents making it possible to influence the pigmentation of the skin and skin appendages, by ensuring optimal transfer of the melanosomes to the keratinocytes, so as to make the skin tone uniform owing to an effect on the SCF/c-Kit signaling pathway. The compounds, compositions, and methods treat or attenuate age-related pigmentation defects and the effects of photoaging on the skin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.