5,7-substituted-imidazo[1,2-C]pyrimidines as inhibitors of JAK kinases
US8962596B2 · kind B2 · utility
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38Claims
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Key dates
| Filing date | Apr 11, 2011 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Feb 2, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of Formula I:and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, R7, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.