Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof

US8962641B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Martin Fleck · Warthausen, DE
• Annekatrin Heimann · Biberach, DE
• Niklas Heine · Eberhardzell, DE
• Bernd Nosse · Biberach an der Riß, DE
• Gerald Juergen Roth · Biberach, DE

Key dates

• Filing date: Apr 7, 2014
• Grant date: Feb 24, 2015
• Expiry date: Apr 7, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new pyrrolidine derivatives of the formulawherein R1 to R3, Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.