Patent · US Active

Causal therapy of diseases or conditions associated with CNS or PNS demyelination

US8962676B2 · kind B2 · utility

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1References

4Claims

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Assignee

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN · IE

Inventors

Mark A. Pickering · Cleveland, US
Keith J. Murphy · Hartford, US

Key dates

Filing date	Oct 22, 2010
Grant date	Feb 24, 2015
Priority date	—
Expiry date	Jan 2, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to the treatment of demyelination as an underlying cause of the disease of multiple sclerosis (MS) in a mammal, the method comprising promoting remyelination of myelination of axonal cells by administering to the mammal a 2-oxopyrrolidine compound having a general formula I:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.