Linezolid intermediate and method for synthesizing linezolid
US8962827B2 · kind B2 · utility
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Key dates
| Filing date | Apr 12, 2012 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Apr 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)—N-(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.