Transgenic non-human animals expressing human blood clotting factors and uses thereof
US8962912B2 · kind B2 · utility
10Cited by
15References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 24, 2011 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Mar 24, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates, in general, to development of non-human transgenic animals expressing a human blood clotting factor, such as Factor VIII, Factor VII, Factor IX and von Willebrand factor. The invention further provides methods of detecting immunogenic events against human blood clotting factor using the transgenic animals described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.