Automated sample-to-microarray apparatus and method
US8965710B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2006 |
| Grant date | Feb 24, 2015 |
| Priority date | — |
| Expiry date | Oct 31, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus having within or as part of a housing; a sample port; a microarray port; a lysis module; a purification module for containing a solid phase for binding of oligonucleotides; a thermocycling module for containing a polymerase chain reaction; a fragmentation module; and a microarray module for holding a microarray and a liquid in contact with the microarray. The apparatus is configured to be coupled to a device for: pumping a liquid through, in order, the lysis, purification, thermocycling, fragmentation, and microarray modules; sonicating any contents of the lysis module; thermocycling the thermocycling module to perform the polymerase chain reaction; heating the fragmentation module to fragment any oligonucleotides contained therein; circulating a fluid over the surface of the microarray; and performing one or more washing or staining steps on the microarray.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.