Trans-base tunnel reader for sequencing
US8968540B2 · kind B2 · utility
31Cited by
5References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 6, 2009 |
| Grant date | Mar 3, 2015 |
| Priority date | — |
| Expiry date | Oct 10, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for reading the sequence of a polymer, consisting of a first electrode and a second electrode, each electrode being functionalized with a reader molecule strongly bonded to the electrodes, but forming weak bonds with a molecule to be sequenced. In particular, the reader molecule is designed to form bonds with at least two points on the target molecule such that the target molecule is trapped between a first reader molecule on one electrode and a second reader molecule on the second electrode, with the overall size of the molecular complex being small enough to permit significant electric current to flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.