Heat shock protein GP96 vaccination and methods of using same
US8968720B2 · kind B2 · utility
5Cited by
73References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2009 |
| Grant date | Mar 3, 2015 |
| Priority date | — |
| Expiry date | Jan 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/63
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a tumor cell genetically modified to express a nucleic acid encoding a secreted form of a heat shock protein (hsp) gp96 polypeptide. The invention also provides a method of stimulating an immune response to a tumor by administering a tumor cell genetically modified to express a nucleic acid encoding a secreted form of a gp96 polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.