Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
US8968742B2 · kind B2 · utility
5Cited by
5References
32Claims
0Family size
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Key dates
| Filing date | Aug 23, 2013 |
| Grant date | Mar 3, 2015 |
| Priority date | — |
| Expiry date | Aug 23, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibody drug conjugates (ADC's) that bind to 158P1D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in glioblastoma, lung cancer, bladder cancer, and breast cancer. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.