Treatment of T-cell mediated diseases
US8969308B2 · kind B2 · utility
12Cited by
100References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2012 |
| Grant date | Mar 3, 2015 |
| Priority date | — |
| Expiry date | Nov 14, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.