Patent · US Active

Diamino heterocyclic carboxamide compound

US8969336B2 · kind B2 · utility

25Cited by
1References
12Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMay 6, 2010
Grant dateMar 3, 2015
Priority date
Expiry dateJan 27, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/113
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Provided is a compound useful as an inhibitor against the kinase activity of EML4-ALK fusion protein.As a result of intensive and extensive studies on compounds having inhibitory activity against the kinase activity of EML4-ALK fusion protein, the present inventors found that the diamino heterocyclic carboxamide compounds of the present invention had inhibitory activity against the kinase activity of EML4-ALK fusion protein. By this finding, the present invention was completed. The compounds of the present invention can be used as a pharmaceutical composition for preventing and/or treating cancer, such as lung cancer, non-small cell lung cancer, and small cell lung cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.