Patent · US Active

Substituted pyrazolone compounds and methods of use

US8969388B1 · kind B1 · utility

1Cited by
14References
23Claims
0Family size

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Key dates

Filing dateJul 19, 2013
Grant dateMar 3, 2015
Priority date
Expiry dateJul 19, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.