Thiophenecarboxamide derivatives as EP4 receptor ligands
US8969394B2 · kind B2 · utility
1Cited by
1References
18Claims
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Assignee
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Key dates
| Filing date | Aug 10, 2007 |
| Grant date | Mar 3, 2015 |
| Priority date | — |
| Expiry date | Jun 25, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to thiophenecarboxamide derivatives of formulae I and II as EP4 receptor ligands, antagonists or agonists, useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, cancer and glaucoma. Pharmaceutical compositions and methods of use are also included. (Formulas I and II).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.