Recurrent gene fusions in prostate cancer

US8969527B2 · kind B2 · utility

Assignees

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US
• The Brigham and Women's Hospital, Inc. · US

Inventors

• Scott Tomlins · Ann Arbor, US
• Daniel Rhodes · Ann Arbor, US
• Arul M. Chinnaiyan · Plymouth, US
• Rohit Mehra · Ann Arbor, US
• Mark A. Rubin · New York, US
• Xiao-Wei Sun · New York, US
• Sven Perner · Bad Wurzach, DE
• Charles Lee · Marlborough, US
• Francesca Demichelis · New York, US

Key dates

• Filing date: May 30, 2012
• Grant date: Mar 3, 2015
• Expiry date: May 30, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/81
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.