Patent · US Active

PIM kinase inhibitors and preparation methods and use in medicinal manufacture thereof

US8969584B2 · kind B2 · utility

4Cited by

2References

11Claims

0Family size

Assignee

Jikai Biosciences, Inc. · CN

Inventor

Yu Ge · Shanghai, CN

Key dates

Filing date	Feb 10, 2014
Grant date	Mar 3, 2015
Priority date	—
Expiry date	Feb 10, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A Pim kinase inhibitor compound having the structure represented by Formula I, and isomers, diastereomers, enantiomers, tautomers, and pharmaceutically acceptable salts thereof. The compounds significantly inhibit Pim kinase activity and can be used to prepare drugs for treating Pim kinase mediated diseases, such as cancers, autoimmune diseases, allergic reactions, or organ transplant rejection. Also provided are methods for preparing the compounds represented by Formula I.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.