Patent · US Active

Process for the preparation of amino acid derivatives

US8969620B2 · kind B2 · utility

0Cited by

1References

14Claims

0Family size

Assignee

UCB Pharma GMBH · DE

Inventors

Alain Merschaert · Brussels, BE
Didier Bouvy · Brussels, BE
David Vasselin · Brussels, BE
Nicolas Carly · Brussels, BE

Key dates

Filing date	Sep 29, 2011
Grant date	Mar 3, 2015
Priority date	—
Expiry date	Sep 29, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process of manufacture of compounds of formula (B) wherein R1, R2 and R3 are as defined for compounds of formula (A), which process comprises hydrogenation of compounds of general formula (A). In particular, the present invention relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (B1), which is useful as an anticonvulsive drug.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.