Patent · US Active

Tissue graft compositions and methods for producing same

US8974810B2 · kind B2 · utility

2Cited by

7References

20Claims

0Family size

Assignee

The Board of Regents of the University of Oklahoma · US

Inventors

Bradley Kropp · Edmond, US
Hsueh-Kung Lin · Edmond, US
Fadee Mandelek · Oklahoma City, US
Brian Grady · Norman, US

Key dates

Filing date	Aug 1, 2011
Grant date	Mar 10, 2015
Priority date	—
Expiry date	Dec 25, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A tissue graft composition is described herein that includes a segment of small intestinal submucosa having at least one nanoparticle incorporated therein such that the permeability of the segment of small intestinal submucosa is altered, thereby providing the segment of small intestinal submucosa with a more substantially uniform structure for cell migration and proliferation. The tissue graft composition may further comprise at least one macromolecule incorporated into the nanoparticle. The tissue graft composition may be utilized in seeded or unseeded methods of tissue repair.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.