Morpholine derivative
US8975252B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 16, 2008 |
| Grant date | Mar 10, 2015 |
| Priority date | — |
| Expiry date | Jun 16, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a morpholine derivative of the formula [I];wherein R1 is a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, a cycloalkyl group or an alkyl group; R2 is a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, an optionally substituted alkylcarbonyl group, an optionally substituted arylcarbonyl group, an optionally substituted heterocyclo-substituted carbonyl group or a cycloalkylcarbonyl group; T is a methylene group or a carbonyl group; R3, R4, R5 and R6 are the same or different and a hydrogen atom, an optionally substituted carbamoyl group or an optionally substituted alkyl group;or pharmaceutically acceptable salts thereof.These compounds are useful as a renin inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.