Substituted pyrazolone compounds and methods of use
US8975282B2 · kind B2 · utility
4Cited by
14References
22Claims
0Family size
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Key dates
| Filing date | Jul 19, 2013 |
| Grant date | Mar 10, 2015 |
| Priority date | — |
| Expiry date | Jul 19, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.