Inhibitor proteins of a protease and use thereof
US8975370B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2004 |
| Grant date | Mar 10, 2015 |
| Priority date | — |
| Expiry date | May 13, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a chimeric inhibitor protein of a protease comprising an inhibiting polypeptidic sequence and at least one polypeptidic sequence of a substrate-enzyme interaction site specific for a protease. Other objects of the invention are to provide a purified and isolated DNA sequence encoding the chimeric inhibitor protein of a protease, an expression vector characterized in that it comprises said purified and isolated DNA sequence, a eukaryotic or prokaryotic host cell transformed with this expression vector and a method of producing a chimeric inhibitor protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.