Labeling reagents for analyte determination and methods and compounds used in making the same
US8975404B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 22, 2007 |
| Grant date | Mar 10, 2015 |
| Priority date | — |
| Expiry date | Jul 9, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6848
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are labeling reagents for analyte determination in a sample, and methods of manufacturing the labeling reagents. By way of non-limiting example, analytes may include one or more of peptides, proteins, nucleic acid molecules, carbohydrates, lipids, steroids and/or small molecules. Also provided are labeled analytes themselves after one or more labeling reagents binds to an analyte. Analytes may be labeled for determination of the analyte by mass analysis, such as by mass spectrometry. Further provided are compounds that may be used in making the labeling reagents and labeled analytes, such as reporter group compounds. Also provided are kits that include at least one labeling reagent, and may further include or more other reagents, containers, enzymes, buffers, a labeled analyte (e.g., as a standard) and/or instructions. Further examples are also possible.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.