Patent · US Active

Mutant delta-9 elongases and their use in making polyunsaturated fatty acids

US8980589B2 · kind B2 · utility

0Cited by

2References

14Claims

0Family size

Assignee

E.I. DU PONT DE NEMOURS AND COMPANY · US

Inventors

Michael W. Bostick · Wilmington, US
Hongxian He · Wilmington, US
Yougen Li · Pennington, US
Quinn Qun Zhu · West Chester, US

Key dates

Filing date	Aug 26, 2011
Grant date	Mar 17, 2015
Priority date	—
Expiry date	Jan 15, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y203/01016
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Mutant delta-9 elongases having the ability to convert linoleic acid [18:2, LA] to eicosadienoic acid [20:2, EDA] and/or α-linolenic [18:3, ALA] to eicosatrienoic acid [20:3, ETrA] are disclosed herein. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding mutant delta-9 elongases, along with a method of making long chain polyunsaturated fatty acids [“PUFAs”] using these mutant delta-9 elongases in oleaginous yeast are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.