Non-retinoid RBP4 antagonist for treatment of age-related macular degeneration and stargardt disease

US8980924B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Konstantin Petrukhin · Collegeville, US
• Janet R. Sparrow · New York, US
• Rando Allikmets · Frederick, US

Key dates

• Filing date: Nov 22, 2011
• Grant date: Mar 17, 2015
• Expiry date: Nov 22, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for treating bisretinoid-mediated macular degeneration in a mammal afflicted therewith comprising administering to the mammal an effective amount of a compound having the structure:or an ester or a pharmaceutically acceptable salt thereof.