Compositions and methods for treating neoplasia, inflammatory disease and other disorders
US8981083B2 · kind B2 · utility
23Cited by
13References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2011 |
| Grant date | Mar 17, 2015 |
| Priority date | — |
| Expiry date | Jan 31, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention features compositions and methods for treating or preventing a neoplasia. More specifically, the invention provides compositions and methods for disrupting the interaction of a BET family polypeptide comprising a bromodomain with chromatin (e.g., disrupting a bromodomain interaction with an acetyl-lysine modification present on a histone N-terminal tail).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.