Process for preparing piperazine

US8981093B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Roland Bou Chedid · Mannheim, DE
• Johann-Peter Melder · Schifferstadt, DE
• Ulrich Abel · Schifferstadt, DE
• Roman Dostalek · Neuleiningen, DE
• Nina Challand · Mannheim, DE
• Bernd Stein · San Diego, US
• Michael Jödecke · Frankenthal (Pfalz), DE

Key dates

• Filing date: Jun 5, 2013
• Grant date: Mar 17, 2015
• Expiry date: Jun 5, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/027
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for preparing piperazine of the formula Iby reacting diethanolamine (DEOA) of the formula IIwith ammonia in the presence of hydrogen and a supported, metal-containing catalyst has been found, wherein the catalytically active mass of the catalyst, prior to its reduction with hydrogen, comprises oxygen-containing compounds of aluminum, copper, nickel and cobalt and in the range from 0.2 to 5.0% by weight of oxygen-containing compounds of tin, calculated as SnO, and the reaction is carried out in the liquid phase at an absolute pressure in the range from 160 to 220 bar, a temperature in the range from 180 to 220° C., using ammonia in a molar ratio to DEOA used of from 5 to 25 and in the presence of 0.2 to 9.0% by weight of hydrogen, based on the total amount of DEOA used and ammonia.