Injection of fibrin sealant using reconstituted components in spinal applications
US8986304B2 · kind B2 · utility
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128References
61Claims
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Key dates
| Filing date | Jun 26, 2012 |
| Grant date | Mar 24, 2015 |
| Priority date | — |
| Expiry date | Aug 3, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.