Implantable collagen devices and related methods and systems of making same
US8986378B2 · kind B2 · utility
26Cited by
45References
22Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 2, 2012 |
| Grant date | Mar 24, 2015 |
| Priority date | — |
| Expiry date | Apr 24, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/54
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention relates to implantable collagen devices made by seeding at least one elongate collagen construct, e.g., comprising at least one elongate synthetic collagen fiber with a plurality of cells and applying a strain and/or stress to the at least one elongate collagen fiber to induce the cells to differentiate into target phenotypes, e.g., tendon or ligament phenotype cells (and/or fibroblasts), typically with an extracellular matrix of collagen to organize into a tissue on the at least one collagen fiber.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.