Patent · US Active

Animal model for the human immune system, and method for producing the same

US8986743B2 · kind B2 · utility

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8Claims

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Assignee

UNIVERSITÄT LEIPZIG · DE

Inventors

Frank Emmrich · Leipzig, DE
Manja Kamprad · Leipzig, DE
Manuela Ackermann · Leipzig, DE

Key dates

Filing date	May 17, 2006
Grant date	Mar 24, 2015
Priority date	—
Expiry date	May 21, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA01K2267/0381
WIPO fieldOther special machines
WIPO sectorMechanical engineering

Abstract

In a method for preparing an animal model for the human immune system in a non-human mammal, human stem cells with hematopoietic potential are transplanted into a non-human mammal. The non-human mammal is conditioned with cell culture supernatant of a culture of human cell lines, cells and/or tissue. The cell culture supernatant is derived from cell lines producing cytokines and other molecular mediators.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.