Substituted piperidines as Par-1 antagonists

US8987248B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Mario Jeske · Solingen, DE
• Dirk Heimbach · Mülheim an der Ruhr, DE
• Susanne Röhrig · Hilden, DE
• Yolanda Cancho Grande · Leverkusen, DE
• Dirk Schneider · Wuppertal, DE
• Ulrich Rester · Wuppertal, DE
• Eckhard Bender · Langenfeld, DE
• Mark Meininghaus · Wuppertal, DE
• Katja Zimmermann · Mülheim an der Ruhr, DE
• Dmitry Zubov · Remscheid, DE
• Anja Buchmüller · Essen, DE
• Georges Von Degenfeld · Leverkusen, DE
• Christoph Gerdes
• Michael Gerisch · Wuppertal, DE
• Mark Jean Gnoth · Mettmann, DE
• Kersten Matthias Gericke · Wuppertal, DE

Key dates

• Filing date: Mar 12, 2010
• Grant date: Mar 24, 2015
• Expiry date: Sep 22, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.