Substituted triazolyl piperazine and triazolyl piperidine derivatives as gamma secretase modulators
US8987276B2 · kind B2 · utility
2Cited by
3References
12Claims
0Family size
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Key dates
| Filing date | Mar 22, 2012 |
| Grant date | Mar 24, 2015 |
| Priority date | — |
| Expiry date | Mar 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with novel substituted triazolyl piperazine and triazolyl piperidine derivatives of Formula (I)wherein R1, R2, R3, R4a, R4b, R5, X, Y1, Y2, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.