Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathway

US8987286B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Hartmut Rehwinkel · Berlin, DE
• Andrea Hägebarth · Berlin, DE
• Oliver Politz · Panketal, DE
• Roland Neuhaus · Berlin, DE
• Ulf Bömer · Glienicke, DE

Key dates

• Filing date: Dec 13, 2011
• Grant date: Mar 24, 2015
• Expiry date: Dec 13, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.